General Manager

About us

LifeMD is a leading digital healthcare company committed to expanding access to virtual care, pharmacy services, and diagnostics by making them more affordable and convenient for all. Focused on both treatment and prevention, our unique care model is designed to optimize the patient experience and improve outcomes across more than 200 health concerns.

To support our expanding patient base, LifeMD leverages a vertically-integrated, proprietary digital care platform, a 50-state affiliated medical group, a 22,500-square-foot affiliated pharmacy, and a U.S.-based patient care center. Our company — with offices in New York City; Greenville, SC; and Huntington Beach, CA — is powered by a dynamic team of passionate professionals. From clinicians and technologists to creatives and analysts, we're united by a shared mission to revolutionize healthcare. Employees enjoy a collaborative and inclusive work environment, hybrid work culture, and numerous opportunities for growth. Want your work to matter? Join us in building a future of accessible, innovative, and compassionate care.

About the role

We are seeking an exceptional General Manager of Metabolic Health & Primary Care to lead and scale a $100M+ revenue, direct-to-consumer healthcare brand delivering longitudinal metabolic health, weight loss and virtual primary care services.

This is a true end-to-end GM role with full accountability for P&L performance, operational execution, clinical quality, and sustainable growth. The GM will oversee a complex, multi-state clinical and operational footprint and will be responsible for driving profitability, retention, and patient outcomes at scale.

This role is best suited for a seasoned healthcare operator with experience leading large, subscription-based or longitudinal care businesses in regulated environments.

Key Responsibilities

P&L and Business Performance:

• Own full P&L responsibility for a $100M+ business, including revenue growth, margin expansion, and operating leverage

• Set and execute annual and multi-year operating plans aligned with company strategy

• Drive performance across LTV, retention, cohort quality, and contribution margin

• Establish rigorous KPI frameworks, operating cadences, and accountability mechanisms

Growth, Retention & Revenue Operations:
• Lead the full DTC growth engine across acquisition, onboarding, engagement, and long-term retention

• Partner with Marketing, Analytics, and Product to optimize CAC efficiency, payback, and scale

• Oversee pricing, packaging, and monetization strategy across metabolic health and primary care offerings

• Identify and scale new programs, service lines, and revenue opportunities

Clinical Operations & Care Delivery:
• Oversee clinical operations in close partnership with Medical Leadership

• Ensure consistent, high-quality, evidence-based care delivery across a national footprint

• Balance clinical excellence, patient experience, scalability, and cost efficiency

• Maintain compliance with all state, federal, and payer requirements

Product & Patient Experience: • Partner with Product and Engineering to set and execute roadmap priorities tied to business and clinical outcomes

• Champion an integrated patient journey across metabolic health and primary care

• Use outcomes data, patient feedback, and operational insights to drive continuous improvement

• Ensure strong clinical-product-ops alignment as the platform scales

Leadership & Organizational Scale: • Lead and develop a senior, cross-functional leadership team across Operations, Clinical, Marketing, Product, CX, and Analytics

• Build organizational structure, processes, and talent density appropriate for a $100M+ platform

• Foster a culture of ownership, execution, and high standards

• Drive change management and organizational maturity as the business scales

Strategic Partnership with CEO & Board: • Serve as a core operating partner to the Founder & CEO

• Translate strategy into executable operating plans and measurable outcomes

• Present performance, risks, and opportunities to the Board and executive leadership

• Anticipate growth constraints and proactively address operational and clinical bottlenecks

Requirements

Basic Qualifications:
• 12+ years of senior operating experience in healthcare, health tech, or complex consumer services
• Direct ownership of a $100M+ P&L or equivalent business unit
• Proven experience scaling subscription-based, longitudinal, or chronic care models
• Strong command of healthcare unit economics, retention, and cohort analytics
• Demonstrated ability to lead large, cross-functional organizations

Preferred Qualifications:
• Experience in metabolic health, obesity medicine, chronic disease management, or primary care
• Background in telehealth, virtual care, or multi-state clinical operations
• Track record of improving profitability, retention, and patient outcomes at scale
• Experience partnering closely with founders, Boards, or PE/VC sponsors• True owner-operator mindset with deep accountability for results
• Highly analytical, data-driven, and execution-focused
• Strong clinical judgment balanced with commercial pragmatism
• Clear, decisive leader who scales people, systems, and culture
• Comfortable operating in regulated, high-growth environments

Benefits

• Health Care Plan (Medical, Dental & Vision)

• Retirement Plan (401k, Roth 401k)
• Life Insurance (Basic, Voluntary & AD&D)
• Flexible PTO Policy
• Paid Holidays
• Short Term & Long Term Disability
• Training & Development