AIQ (Analytical Instrument Qualification) SME

cGxPServe
Skaneateles Falls, NY
Responsibilities:
  • Serve as the technical SME for qualification of analytical equipment in manufacturing setup.
  • Author and execute qualification protocols (URS, DQ, IQ, OQ, PQ) in accordance with GAMP 5, FDA 21 CFR Part 11, and EU Annex 11 requirements.
  • Lead and support equipment lifecycle activities, including requalification, decommissioning, and periodic review.
  • Ensure data integrity compliance in computerized systems interfaced with analytical instruments.
  • Collaborate with Quality, Validation, Metrology, IT, and Lab teams to define qualification strategies for new and upgraded equipment.
  • Maintain traceability between user requirements, functional specifications, and qualification deliverables.
  • Provide guidance on change control and impact assessments for equipment modifications or upgrades.
  • Support audits and inspections by presenting qualification documentation and providing SME-level responses.
  • Drive continuous improvement in qualification practices and documentation templates across global sites.
Requirements:
  • Bachelor's or master's degree in chemistry, Engineering, Life Sciences, or a related technical field.
  • Experience in analytical equipment qualification, preferably in a GMP-regulated medical device or pharmaceutical environment.
  • In-depth understanding of.
  • FDA regulations (21 CFR Parts 820, 210/211, 11).
  • GAMP 5 and ISO 13485.
  • Data integrity principles (ALCOA+).
  • Experience qualifying and maintaining Manufacturing equipment.
  • Familiarity with electronic document systems, validation tools, and computerized system validation.
  • Certification in Lean Six Sigma, ASQ, or ISPE.
  • Experience supporting global harmonization of validation practices across multi-site environments.
  • Working knowledge of medical device testing requirements, especially for infusion devices, sensors, or diagnostic platforms.
Posted 2025-08-07

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