Principal Cloud Development Security and Operations Engineer

Regeneron
Tarrytown, NY

Build our future together:

The Regeneron Genetics Center Information Technology team is looking for a passionate Principal Cloud Development, Security, and Operations Engineer with strong technical ability, communication, and collaboration skills. You will be responsible for the design and implementation of cloud infrastructure, automation, security controls, and compliance processes on Amazon Web Services, supporting data, High-Performance Computing, Artificial Intelligence, and microservice platforms used by research scientists and bioinformaticians. You will work hands-on to build and implement cloud Development, Security, and Operations solutions, embed security into system design, and provide technical support and guidance to end users and internal teams. You will also provide technical mentorship for Lead and Senior Development, Security, and Operations engineers and coordinate with Information Security, Privacy, and internal Information Technology teams to ensure security, scalability, and reliability of the Regeneron Genetics Center cloud platform.

When & where:

Location: Tarrytown, NY

Work model/flexibility: 4 days onsite

Discover your role:

  • Design and implement infrastructure-as-code, automation scripts, and Continuous Integration/Continuous Delivery pipelines supporting data, High-Performance Computing, Artificial Intelligence, and microservice platforms on Amazon Web Services.

  • Embed security controls into system design and implementation, including Identity and Access Management policies, network segmentation, secrets management, and compliance validation pipelines.

  • Design and implement tools to automate operational processes across Regeneron Genetics Center's cloud and systems engineering platforms.

  • Support all audit-related activities, including providing evidence and remediation of findings for the Regeneron Genetics Center cloud platform.

  • Develop and implement continuous delivery systems and Continuous Integration/Continuous Delivery methodologies for Regeneron Genetics Center's systems engineering platforms using both Amazon Web Services services and GitHub Actions, Actions Runner Controller self-hosted runners on Elastic Kubernetes Service, and Static Application Security Testing/Dynamic Application Security Testing integration.

  • Recommend and deploy monitoring, metrics, and logging systems on Regeneron Genetics Center cloud engineering platforms.

  • Identify and implement opportunities to build systems that are highly available, scalable, and self-healing.

  • Develop Standard Operating Procedures and configure cloud services to support compliance validation.

  • Provide technical support, training, and documentation to end users and research teams using Regeneron Genetics Center's data, High-Performance Computing, Artificial Intelligence, and microservice platforms.

This role requires:

  • Bachelor's Degree in Computer Science or a related field.

  • 8+ years of in-depth Amazon Web Services experience and relevant security certifications.

  • Hands-on experience designing and implementing cloud infrastructure automation, Continuous Integration/Continuous Delivery pipelines, infrastructure-as-code, and security controls.

  • Solid understanding of cloud security posture, including Identity and Access Management, network segmentation, secrets management, compliance validation, and security-by-design principles.

  • Experience supporting data, High-Performance Computing, Artificial Intelligence, or microservice platforms in a technical or user-facing capacity.

  • Knowledge of core Amazon Web Services including Elastic Compute Cloud, Elastic Block Store, Simple Storage Service, Elastic Load Balancing, Relational Database Service, Elastic Kubernetes Service, and Identity and Access Management.

  • Tangible experience with Linux administration and automation of security controls and compliance validation.

  • Experience with monitoring tools such as Splunk, Grafana, and Prometheus.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.



Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.



As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.



For jobs in Canada: this posting is for an existing position.



Salary Range (annually)

$128,600.00 - $210,000.00
Posted 2026-07-30

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