Assistant/Associate Professor - Research - Laboratory of Immunity and Tissue Regeneration - New York, NY

We are excited to invite applications for a non-tenure-track Assistant Professor position in the Laboratory of Immunity and Tissue Regeneration at the Icahn School of Medicine at Mount Sinai ().

This is a unique opportunity to join a vibrant, interdisciplinary environment at one of the world’s leading academic medical centers, located in the heart of New York City. Mount Sinai is a premier hospital system and research hub, offering unparalleled access to diverse patient populations, cutting-edge clinical programs, and world-class scientific resources.

We are seeking an exceptional early-career scientist with expertise in molecular biology (cloning, CRISPR, epigenetics) and in vivo models who is eager to push the boundaries of discovery. The position offers the chance to explore the molecular drivers of tissue repair, chronic inflammation, inflammatory memory, and their impact on disease relapse and tissue dysfunction.

The successful candidate will have the independence to lead high-impact projects with both fundamental and translational dimensions, while benefiting from extensive collaborations across Mount Sinai and with external partners in academia, biotechnology, and the pharmaceutical industry. This role provides an outstanding platform for scientific creativity, career development, and meaningful contributions to advances in human health.

• Lead cutting-edge research: Design, plan, and execute molecular, in vitro, and in vivo experiments to uncover mechanisms of inflammatory memory, epigenetic regulation, and tissue adaptation in chronic inflammation, with a focus on skin and other barrier tissues.
• Innovate at the bench: Develop and refine molecular and genomic tools, including cloning strategies, chromatin and epigenetic assays (e.g., chromatin accessibility, histone modifications, enhancer/promoter regulation), single-cell epigenetics, and spatial transcriptomics, to dissect regulatory networks.
• Drive funding success: Lead or co-lead grant proposals (NIH, foundations, etc.), manage reporting and progress updates, and contribute to long-term resource planning.
• Manage operations: Oversee day-to-day laboratory activities along-side the laboratory manager, supervise technical staff, coordinate with Icahn core facilities, and ensure compliance with IRB, IACUC, and other institutional guidelines.
• Mentor and inspire: Train junior scientists, postdocs, and collaborators in molecular and in vivo techniques, data interpretation, and rigorous experimental design.
• Build collaborations: Coordinate interdisciplinary studies with internal and external partners, including clinical teams, computational/omics cores, and laboratories focused on inflammation and regenerative biology.
• Advance knowledge: Publish high-impact manuscripts, present at national and international conferences, and help elevate the program’s scientific profile.

• PhD, MD, or equivalent in Molecular Biology, Immunology, Epigenetics, or a related field
• Minimum of 4 years of postdoctoral research experience with demonstrated expertise in molecular biology (cloning, genome editing, epigenetics) and in vivo biology (murine models, human tissue)
• Proven ability to design and execute complex experiments, including epigenetic profiling, chromatin/imaging assays, and in vivo functional studies
• Strong publication record in relevant fields
• Demonstrated ability (or clear potential) to secure independent funding
• Excellent communication and organizational skills
• Commitment to collaboration within a dynamic, multidisciplinary research environment

Compensation range from 105K to 150K (not including bonuses / incentive compensation or benefits).

Salary Disclosure Information:
Mount Sinai Health System provides a salary range to comply with the New York City law on Salary Transparency in Job Advertisements. Actual salaries depend on a variety of factors, including experience, specialties, historical productivity, historical collections, and hospital/community need. As such, an actual salary may fall closer to one or the other end of the range, and in certain circumstances, may wind up being outside of the listed salary range. The salary range listed is for full-time employment and does not include bonuses / incentive compensation or benefits.

Please specify Job Title of interest and send CV with Cover Letter to:
Physician Recruitment Department
Mount Sinai Health System
[email protected]

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.