Post-Doctoral Researcher Supporting Embedded Faculty Member, Minna Lee (with the Sarat Chandarlapaty Laboratory)

About Us

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.

The Chandarlapaty lab is comprised of a multidisciplinary team investigating the basis for therapeutic response and resistance in breast cancer.

• A postdoctoral research position is opening to specifically study the mechanisms underlying the response of homologous recombination deficient (HRD) breast cancers to endocrine therapies
• The project will involve development and validation of high-fidelity models of endocrine-responsive HRD breast cancer using advanced genome engineering approaches of both 2D and 3D culture systems, as well as molecular and functional assays related to DNA damage and repair and endocrine therapy response and resistance.
• The successful candidate will be required to work in collaboration with other members of the laboratory as well as several clinical and translational teams with shared interests.
• Position is supported by funding from the National Cancer Institute and the Breast Cancer Research Foundation

Key Requirements

• PhD in cancer biology, genetics, cell biology, or pharmacology.
• Track record of publication in areas of cancer biology, genetics, cell biology, or pharmacology.
• Demonstrated ability to design, execute and interpret experiments independently.
• Ability to work collaboratively in a multidisciplinary team environment.

Application Requirements

Core Skills:

• Strong expertise with mammalian cell culture and genetic manipulation
• Demonstrated expertise in CRISPR/Cas9 genome editing
• Solid background in molecular biology techniques (PCR, western blot, sequencing based validation)
• Experience with organoid culture or other 3D model systems preferred
• Bioinformatics experience for analysis of sequencing or functional genomics data preferred
• Interest in translational research and collaboration with clinical teams

Application Instructions

Submit C.V., letter of interest, and references in your application submission to: Sarat Chandarlapaty, MD, PhD

[email protected]

Pay Range: $72,000 – $96,405

Helpful Links

• MSK Compensation Philosophy
• Review Our Great Benefits Offerings

Pay Range: $0.00 - $10,000,000.00

FSLA Status: Exempt

Closing

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.